2024-03-29T08:45:24Z
https://ejom.journals.ekb.eg/?_action=export&rf=summon&issue=162
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
EVALUATION OF DISABILITY DUE TO B AND/OR C VIRAL HEPATITIS AMONG HEALTH CARE WORKERS IN CAIRO UNIVERSITY HOSPITALS
Abo El-Ata
A.
Zayet
H.
Ahmed
H
Abdel-Rafaa
S.
Fawzi
M.
This study was conducted on 958 workers in Cairo University Hospitals where hepatitis markers (Hepatitis C virus antibodies and Hepatitis B surface antigen) were investigated for all of them. The seropositivity of HCVantibodies and HBsAg were found to be 10% and 0.93% respectively of the total studied patients. All positive cases were called for further evaluation but only 66 patients agreed to continue such an evaluation. All patients were assessed clinically, and with biochemical tests (ALT, AST, bilirubin and alkaline phosphatase) as well as with abdominal ultrasonographythen an impairment rating was calculated for each subject using The American Medical Association (AMA) Guides for Evaluation of Permanent Impairment and the Australian Commonwealth Employees' Rehabilitation and Compensation Act.Of the 66 patients, about 40.9% were asymptomatic and 71.21% were apparently normal on clinical examination whereas 40.91% of patients had elevated serum ALT and 76% showed abnormal hepatic echo pattern that could be attributed to chronic viral hepatitis. The sonographic changes were found to be insignificantly related to job duration, type of job or type of hepatitis. Also, no statistically significant differences
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https://ejom.journals.ekb.eg/article_606_f5ae9ea8a655a9fa327cbb694ef4c1d9.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
EFFECT OF CYTOCHROME P450 1A1 (CYP1A1)POLYMORPHISM ON ASPHALT EXPOSURE - RELATED BIO-MARKERS
Farahat
A
Helal
F.
Abdel
N.
Rashed
A.
Asphalt fumes contain polycyclic aromatic compounds (PAC). There is a possibility of long-term health effects following chronic exposure by inhalation or skin contamination in asphalt road pavers. Objective: This study aimed at exploring the relationship between urinary 1-OH pyrene as a marker of internal dose of PAHs exposure and serum P53 protein as a response marker with the genetic polymorphism of CYP1A1 as a susceptibility marker among asphalt exposed workers. Methods: This work included 70 male individuals who were divided into an asphalt exposed group (n=43) and a matched control group (n=27). The exposed group was further subdivided into a group of paving and mixing (n=24) and a group of roller and vehicle drivers (n=19). Every participant was subjected to polymerase chain reaction (PCR) technique to detect the different genotypes of CYP1A1 gene and the expression of the p53 gene mutation. Besides, estimation of urinary 1-hydroxy pyrene (1-OHP) and serum level of mutant p53 protein was done as a PAHs exposure and response biomarkers, respectively. Results: CYP1A1*2A (Valine / Valine) was found to be the most prevalent CYP 1A1 genotype among both exposed and control groups. It was associated
Asphalt-PAHs-CYP1A1- CYP1A1*2A-CYP1A1*1- CYP1A1*2CPolymorphism-P53 gene mutation- Urinary 1-OH Pyrene
2007
01
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29
49
https://ejom.journals.ekb.eg/article_613_69b77625b3b3980e772f947c9222c3b7.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
HEPATITIS FOLLOW UP AMONG PESTICIDE FORMULATORS
Amr
M.
Salem
M.
Attia
DI.
Samir
M.
The liver is the target organ of many occupational and environmental agents and plays a central role in their etoxification as well as the elimination of many toxic chemicals and/or their metabolites . A previous study was done three years ago on 389 subjects in a chemical factory for pesticide formulators, it revealed that there was a significant seroprevalence ofHCV & HBV among studied workers as well as significant elevation of ALT enzymes among both seropositive and seronegative HCV & HBV . This work was done on 150 selected workers from a previous study three years ago in a chemical factory formulating pesticides. All selected subjects were assessed by clinical examination regarding mplications and risk factors of hepatitis, laboratory investigations and abdominal ultrasonography.We concluded from this study that there is an increase in the curve of progression of chronic liver disease among studied subjects on follow up and this may be due to presence of another contributing factor which is chronic exposure to pesticides.
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https://ejom.journals.ekb.eg/article_615_aa02f3db0cbe5b57e7430eb9b807d8be.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
SPIROMETRIC CHANGES IN RELATIONSHIP TO SERUM CHOLINESTRASE LEVELS FOR WORKERS IN A PESTICIDE-PROCESSING FACTORY
Abou Salem
E.
Abdel-Rasoul
M.
Al-Batanony
A.
Background: occupational exposure to pesticides produces health disorders for exposed individuals by inhalation, skin contact, or ingestion. Aim: to study the spirometric changes in relationship to serum cholinestrase level among a group of workers employed in a pesticides processing factory. Subjects and methods: Fifty six pesticide-exposed males and 56 non-exposed male workers (as a control group) were chosen for this study. Each participant was subjected to a questionnaire including personal data; medical examination; serum cholinestrase level; and spirometric measurements (FVC%, FEV1%, FEV1/ FVC% & FEF75-85 %). Results : the respiratory manifestations as cough, expectoration, dyspnea, wheezes and crepitations were significantly more prevalent among pesticide-exposed workers than controls. Significant decrease in the serum cholinestrase level and in mean values of spirometric measurements for FVC%, FEV1%, FEV1/ FVC% & FEF75-85 % were found among pesticide-exposed workers than the control group. The decrease in studied spirometric mean values among pesticide-exposed workers was associated with increased length of duration of work. Also, there was a significant positive correlation between mean values of serum cholinestrase (ChE) among exposed workers and studied spiromet-
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https://ejom.journals.ekb.eg/article_616_9d6ab92d7b4a24c7dd73a013a62da96f.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
EVALUATION OF OCCUPATIONAL EXPOSURE TO GLUTARALDEHYDE AMONG ENDOSCOPY NURSING STAFF IN MENOUFIYA UNIVERSITY HOSPITAL
Al-Batanony
A.
El-Shafie
K.
Background: Glutaraldehyde is the best disinfectant for fibreoptic endoscopes. A number of studies has reported that glutaraldehyde is an irritating substance affecting ocular and nasal mucosae and may give rise to sensitization. Cases of allergic dermatitis, rhinitis, epistaxis, asthma, lacrimation and headache were also reported amongexposed workers. Aim of the work: This study aimed at finding the nature and prevalence of workrelatedsymptoms (WRSs) among nurses working in endoscopy units and assessment of the concentration of glutaraldehyde in the work environment. Subjects and Methods: Thirty non-pregnant non-smokers nurses occupationally exposed to glutaraldehyde (GA) in various endoscopy units in Menoufiya University hospital were chosen as subjects of this study. An equal number of nurses never occupationally exposed to GA were chosen as a non-exposed group. The Medical ResearchCouncil Respiratory Questionnaire was used to record work-related symptoms,spirometric measurements and laboratory measurement of total immunoglobulin
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https://ejom.journals.ekb.eg/article_618_6eef148a72976a8ee74f7c934d2ba13e.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
LIPID PEROXIDATION DUE TO TRI-VALENT CHROMIUM (CR3) AMONG TANNERY WORKERS
El Samra
H.
Hussein
A.
Farahat
A.
Samir
M.
Chrome tanning is the most widely used tanning system worldwide because of its advantages. Occupational exposure to chromium among tannery workers is mainly to the inorganic Cr (III) form. Aim of work: The study aimed at monitoring the level of chromium in both blood and urine among tannery workers and clarifying the effect of increased chromium level in the body on the level of free iron in blood and transferrin based on the fact that both chromium and iron compete for binding sites on transferrin protein. Lipid peroxidation was estimated through measuring the level of malondialdehyde(MDA) in blood. Methods : This work has been carried out in five small- to medium-sized Egyptian tanneries, in Misr Al kadema area in Cairo. The study population was composed of an exposed group (n=50) and a matched control group (n= 30).Every subject was subjected to estimation of chromium and iron in both blood and urine. Measurement of transferrin , MDA in blood and blood haemoglobin were done. Results: There was significant increase in the level of the measured parameters among the exposed subjects compared to controls except for haemoglobin which was insignificantly lower among the exposed group. There was significant positive correlation between chromium in urine and blood on one hand and free iron in blood and urine and serum MDA on the other. Also there was significant negative correlationbetween chromium in urine and blood on one hand and haemoglobin on the other.
tanning industry
Cr (III)
transferrin
free iron
Lipid peroxidation
MDA
haemoglobin
2007
01
01
87
105
https://ejom.journals.ekb.eg/article_619_3d15175c6e7d3ee8004e5e74e0d02ea1.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
ASSESSMENT OF RESPIRATORY AND RENAL FUNCTIONS AMONG GAS METAL ARC WELDERS AND THEIR RELATIONS WITH CHROMIUM EXPOSURE
Helal
F.
Arafaa
M.
Afify
M.
Background: Welding is the most common way of permanently joining metal parts. Welders use many types of welding equipment set up in a variety of positions. Arc welding is the most common type. Welding, soldering, and brazing workers often are exposed to a number of hazards, including the intense light created by the arc, poisonousfumes, and very hot materials.Objective: The aim of the present study was to investigate some of the health hazards among gas metal arc welders with special emphasis on renal and lung examination and to monitor the level of chromium in blood and urine, and studying its relation with the renal condition. Our aim was also to detect early renal affection by measuring of B2 microglobulin in urine. Subjects and methodology: This study was conducted in three welding shops in El Manial, and El Maadi, in Cairo. The study was accomplished during the months of October and November,2006.The studied group comprised 18 workers in the metal arc welding shops. They were adult men aged between 18-42 years (26.5 ±7.8), working on the basis of 12 hours/day with one day off per week. None of the workers used any protectiveequipment during working hours. A referent group of 20 males matched for age that ranged from 21-41 yrs., (26.2±6.38), sex, socio-economic status, smoking
Metal arc welders- Chromium- B2 microglobulin- MFF
2007
01
01
107
121
https://ejom.journals.ekb.eg/article_620_72bf1db585a767cd7c0ddb75292e27d8.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
CHROMOSOMAL ABERRATIONS IN WORKERS OCCUPATIONALLY EXPOSED TO CHROMIUM, NICKEL AND COBALT
Ananian
B.
Siha
S.
Hussein
H.
Introduction: Combined exposure to chromium, nickel and cobalt occurs in many occupations as dental laboratory technicians, electroplating workers and welders. Dental laboratory technicians whom are the main concern in our study are exposed to chromium, nickel and cobalt metal alloys during casting, finishing and polishing of dental prosthesis (e.g. bridges, crowns, partial and complete dentures) and also to small amount of molybdenum, silica beryllium, boron and carbon. The objective of this work was to evaluate the magnitude of exposure to these metals among dental laboratory technicians and their genotoxic effects.Subjects and methods: The study included 30 dental technicians (24 male & 6females) and 20 comparable control subjects (15 male and 5 females) selected from outpatient clinic and nursing staff in Kasr ElAini hospital. Both groups were subjected to a prepared questionnaire including present, occupational, past and family history , measurement of serum chromium, nickel and cobalt levels, assessment of the chromosomal aberrations in the peripheral blood lymphocytes and measurements of the air levels of the chromium, nickel and cobalt at the work place.
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https://ejom.journals.ekb.eg/article_621_751560690cdad8bbaec9d0a7f8c9f560.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
EFFECT OF EXERCISE AND MANUAL PHYSICAL THERAPY ON SHOULDER FUNCTION AMONG SLAUGHTERHOUSE WORKERS WITH SHOULDER IMPINGEMENT SYNDROME.
El-Laithy
N.
El-Toukhy
A.
Amar
A.
Asal
M.
This study was carried out in a slaughterhouse in Zagazig City during the year 2005-2006 among a group of 115 slaughterhouse workers selected randomly and performing sustained intensive manual work. Another group of 80 clerks working in Zagazig Faculty of medicine performing light manual work was selected randomly as a control group. The study was done in 2 stages : The 1st stage was a comparative cross-sectional study, aiming to determine the prevalence of shoulder impingement syndrome ( SIS) among the study workers.The 2nd stage was an intervention study, done to assess the effect of exercise and manual physical therapy program on shoulder function among workers with shoulderimpingement syndrome. A total number of one-hundred and ninety five workers were interviewed using a preconstructed questionnaire. Those workers who had recurrent 143 Egyptian Journal of Occupational Medicine, 2007; 31 (1) : 143 - 162144 El-Laithy N. et. al shoulder pain during the previous 3 months or more were subjected to standardizedphysical examination using impingement sign, assessment of shoulder function and magnetic resonance imaging to those clinically diagnosed as SIS. Also an intervention program of exercise and manual therapy for a period of 6-weeks was carried out to those workers with SIS.he results revealed that the prevalence of SIS was higher among the laughterhouseworkers (13.9 % ) compared to the control workers(2.5%). SIS symptoms and signs were more frequently recorded among the slaughterhouse workers when compared with the controls. Also among those currently complaining of SIS symptoms or those who has had SIS signs, only 15.6% and 2.5% have positive impingement sign among slaughterhouse workers and their controls respectively. The most reliable findings of magnetic resonance imaging were the presence ofindentations upon the subacromial fat denoting impingement in 12 patients (66.7%),supraspinatus tendonitis with indentation upon subacromial fat denoting impingement in 4 patients (22.2%) & left supraspinatus tear in 2 patients (11.1%) from 18 slaughterhouse workers diagnosed clinically as SIS and supraspinatus tendonitis with impingementin 2 patients (100.0%) from the control group with a total percentage of 13.9% and 2.5% workers with SIS among slaughterhouse workers and their controls respectively. Studying some personal and occupational factors thought to be related to the prevalence of SIS revealed that, SIS was prevalent in middle aged workers who smoke and were worked in the current occupation for more than ten years.The results of the intervention program illustrated that there were significant improvement in range of motion, pain, strength and function of the shoulder in workers with SIS after 6- weeks of exercise and manual physical therapy program.In conclusion, sustained intensive manual work such as in slaughterhouse workers was associated with high frequency of SIS. A 6 week exercise with manual physicaltherapy program in patients with SIS was resulted in improvement of range of motion, pain and function of the shoulder. So, work organization especially reduction of exposure time and early intervention are needed in tasks in which there are combinations of force, repetition and sustained arm elevation.
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2007
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https://ejom.journals.ekb.eg/article_623_f5e5455b175504d43ade9592e05de097.pdf
Egyptian Journal of Occupational Medicine
Egypt. J. Occup. Med.
1110-1881
1110-1881
2007
31
1
IMMUNE, REPRODUCTIVE, AND CYTOGENETIC CHANGES AMONG WASTE INCINERATION WORKERS AT THE COMPOST FERTILIZER PLANT IN ZAGAZIG CITY
El-Laithy
N.
Abbas
A.
El-Hawary
A.
Sabik
M.
Eassa
M.
El-Sebaey *
A.
Background: The adverse health effects associated with mass burn incineration are of great concern as large population groups and workers may be exposed to derived toxic substances. Objectives: 1) determining some of the immunological, reproductive,and cytogenetic changes among workers exposed to waste incineration emissions at the waste incineration area of the compost fertilizer plant in Zagazig City, 2)determining the blood lead levels of the studied workers, and 3) assessing airborne particulate matter concentrations at the open dump and waste incineration area. Subjects and methods: This comparative cross-sectional study was conducted on 42 waste incineration workers, who were exposed to waste incineration emissions at the compost fertilizer plant in Zagazig City and a non-exposed control group (51 workersfrom 2 sweet factories). All workers were subjected to questionnaires, clinical examinations,and laboratory investigations, that included blood lead levels estimation, immunoglobulins estimation, flow cytometric analysis, and conventional cytogenetic analysis; While, only 12 workers from both groups agreed to perform semen analysis. Also, sampling of respirable airborne particulates, at the open dump and waste incineration area, was done. Results: Significantly higher percent of waste incineration workers had past history of recurrent infections suggesting depressed immune responsecompared to the controls. Also, married waste incineration workers had significantly higher complaints from secondary infertility, decreased libido, and congenital anomalies in their children compared to the married controls. mmunoglobulins and flow cytometric results demonstrated a significant increase in both CD8 and CD 25+cells (P<0.05) and a significantdecrease in CD4/CD8 ratio (P<0.05) among waste incineration workers compared to the control group; while there were no significant differences detected regarding immunoglobulins profile, CD3, and CD4. The results of semen analysis illustrated that, waste incineration workers had a significant decrease in the total sperm count and sperm motility and a significant increase in the percentage of abnormal forms of sperms than did the controls. The conventional cytogenetic analysis of this study revealed significantly higher frequency of chromosomal aberrations (dicentric chromosomes and accentric fragment) among waste incineration workers compared to the controls (P<0.001). Moreover, waste incineration workers with chromosomal aberrations had significantly longer duration of employment thanthose without chromosomal aberrations (P<0.05); while, smoking had no significant effect on the results of their cytogenetic analysis. Waste incineration workers were found to have significantly higher blood lead levels (11.8 + 3.4 μg/dl) when compared to the controls (7.8 ± 1.85 μg/dl) (P<0.001). Finally, the average concentrationof the respirable particulate matter in the open dump and waste incineration area was 0.47 mg/m3, which exceeds its threshold limit value (TLV). Conclusion and recommendations:unprotected occupational exposure to waste incineration emissions can cause serious immunological, reproductive, and cytogentic changes. So, a well designed control program is recommended, which should include; avoiding open burning of waste products and promote the use of non- incineration treatment technologies,using incinerators equipped with proper emission control system, continuous environmental and biological monitoring for lead, particulate matter, and other hazardous materials, using immune system parameters, semen quality, and chromosomal aberrations as biomarkers of effect in such workers, and using suitable protectiveequipment during work.
2007
01
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163
183
https://ejom.journals.ekb.eg/article_624_4a99f1b5dcf3052e580f2d5c898e9d74.pdf