Na., M., H., H., MM., S., ShS., A. (2010). SEMEN QUALITY AND REPRODUCTIVE ENDOCRINAL FUNCTION WITH REGARD TO BLOOD LEAD LEVEL IN INFERTILE PAINTERS. Egyptian Journal of Occupational Medicine, 34(1), 57-69. doi: 10.21608/ejom.2010.687
Mansour Na.; Hosni H.; Shatta MM.; Azab ShS.. "SEMEN QUALITY AND REPRODUCTIVE ENDOCRINAL FUNCTION WITH REGARD TO BLOOD LEAD LEVEL IN INFERTILE PAINTERS". Egyptian Journal of Occupational Medicine, 34, 1, 2010, 57-69. doi: 10.21608/ejom.2010.687
Na., M., H., H., MM., S., ShS., A. (2010). 'SEMEN QUALITY AND REPRODUCTIVE ENDOCRINAL FUNCTION WITH REGARD TO BLOOD LEAD LEVEL IN INFERTILE PAINTERS', Egyptian Journal of Occupational Medicine, 34(1), pp. 57-69. doi: 10.21608/ejom.2010.687
Na., M., H., H., MM., S., ShS., A. SEMEN QUALITY AND REPRODUCTIVE ENDOCRINAL FUNCTION WITH REGARD TO BLOOD LEAD LEVEL IN INFERTILE PAINTERS. Egyptian Journal of Occupational Medicine, 2010; 34(1): 57-69. doi: 10.21608/ejom.2010.687
SEMEN QUALITY AND REPRODUCTIVE ENDOCRINAL FUNCTION WITH REGARD TO BLOOD LEAD LEVEL IN INFERTILE PAINTERS
3Dept. Of Chemical Pathology, Faculty of Medicine, Cairo University
4Dept. Of Urosurgery, 6th October University
Abstract
Objective: To investigate the effect of lead on semen quality and reproductive endocrinal function among infertile painters. Methods: A retrospective cohort study was performed using data collected from 27 infertile painter recruited through infertility clinic and Andrology inpatient department. All participants were subjected to semen analysis, measuring of blood lead level ( BPb ) and serum level of endocrinal parameters including follicle-stimulating hormone(FSH), luteinizing hormone(LH), testosterone(T) and prolactin (pl). Results:-significant decline in the spermatic count and motility in those with longer duration of exposure(>15y) without significant duration influence on BPb and serum level of FSH, LH, PT and T. In addition, significant negative correlation of BPb and spermatic count and motility was found, while all endocrinal parameters showed non-significant correlation. Further analysis of the results revealed statistically significant decline in spermatic motility and increase in testosterone level among the group of BPb > 20 μg/dl beside the observed reduction in the count, which did not reach the significant level. While other endocrinal parameters showed non statistically significant differences. In conclusion, infertile painters were at risk of Lead related influence on semen quality specially spermatic motility and increased testosterone level without significant affection of other reproductive endocrinal parameters.
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